According to surveys, 53% of entrepreneurs work more than 12 hours a day, with some even working up to 16 hours, resulting in chronic fatigue. However, since entrepreneurs are at the core of their businesses, they continue to work hard despite their exhaustion. Therefore, they are eager to be energized every day to perform better in their work.

And at this point, scientists have found the perfect solution to this problem: supplementation with NAD+ related supplements - NMN.So, how does NMN do this? Let's start with the source of cellular energy.


1. The Body’s Energy Factory—Mitochondria

Our bodies get their energy from cellular energy, and cellular energy is missing the work of mitochondria.

As we all know, the human body consists of 6 billion trillion cells, and the health of the cells directly affects human health.

And 95% of the energy required by the cell from the mitochondria, it can synthesise adenosine triphosphate (ATP), for the cell to provide life energy, but also regulates the growth of the cell, apoptosis, therefore, the mitochondria have ‘the engine of life,’ the name.

Therefore, if you feel energetic and full of energy throughout the day, you can't do it without the mitochondria ‘working hard to generate electricity’.

On the other hand, if the mitochondria dysfunction, it will cause cellular energy, cellular communication is blocked, triggering a variety of health problems, but also make the body accelerated aging.


2. NAD+: A Key Factor Influencing Mitochondrial Function

Since mitochondrial function is so important, what factors contribute to mitochondrial dysfunction?

In this study published in 2015, it was mentioned that one contributing factor to mitochondrial abnormalities is the absence of nicotinamide adenine dinucleotide (NAD+).

In mitochondria-mediated energy production and cellular function, NAD+ is an important enzyme in the production of adenosine triphosphate (ATP), the most important part of cellular respiration. Each cell in the body requires thousands of ATP, and NAD+ helps cells get the energy they need for this purpose.

In 2012, a study led by Professor Shinichiro Imai of the University of Washington, USA, comprehensively examined the ‘dynamic regulation of NAD+ metabolism in mitochondria’, confirming the close relationship between NAD+ levels in mitochondria and mitochondrial function.

But as we age, the level of NAD+ available to the body declines considerably. In contrast, we noticeably feel less energy and stamina than before.


3. NMN Can Significantly Enhance Mitochondrial Function

NMN, as a direct precursor to NAD+, has been confirmed in several studies to rapidly elevate NAD+ levels in our bodies, which in turn enhances mitochondrial function.

Scientific research published in 2020 by a team of researchers led by the University of Minnesota confirmed the boosting effect of NMN on mitochondrial function.


This study was conducted on a type of cell that is extremely mitochondria-dependent - the retinal pigment epithelium (RPE), which is responsible for maintaining human vision.

The energy used by this cell comes essentially exclusively from the mitochondria, so that as soon as there is a problem with mitochondrial function (e.g., aging), this cell dies, causing age-related macular degeneration.

Researchers have found that NMN comprehensively improves mitochondrial function in the RPE and exhibits a very rapid onset of action, reaching peak effect within 24 hours of use. This improvement is achieved primarily by increasing ATP production capacity.

In practical applications of NMN, this rapid boost in energy can be clearly felt. Many people experience a swift increase in cellular energy levels after taking NMN, as if they have overnight returned to a youthful, energetic state.