In addition to its anti-aging properties, NMN has a variety of other potential benefits for women, to give you a detailed overview:
I. Improvement of multiple skin problems
NMN effectively repairs a wide range of skin problems by supplementing NAD+ (Nicotinamide Adenine Dinucleotide), activating SIRT1 protein deacetylase, enhancing antioxidant capacity and promoting angiogenesis in a variety of ways.
NAD+ plays a key role in the cell and is involved in processes such as energy metabolism, DNA repair and cell signalling. As we age, the level of NAD+ in skin cells gradually decreases, leading to signs of aging such as sagging, wrinkles, and dryness of the skin.NMN, as a precursor substance of NAD+, can be efficiently utilised by the cells to increase the level of intracellular NAD+, thus activating the energy metabolism and repair mechanism of the skin cells.
SIRT1 is a NAD+-dependent deacetylase that plays an important role in the anti-aging process of the skin. When NMN increases NAD+ levels, the activity of SIRT1 is also enhanced. Activated SIRT1 regulates the expression of a variety of genes related to skin aging, promotes collagen synthesis and cell regeneration, and reduces the production of free radicals, thereby improving skin elasticity, reducing wrinkles, and enhancing overall skin quality.
In addition, NMN has an antioxidant effect that scavenges free radicals in the body and reduces skin damage caused by external factors such as UV rays and pollution. By enhancing the skin's antioxidant capacity, NMN helps to slow down the skin's aging process, keeping it young, smooth and healthy.
II. NMN restores ovarian rejuvenation
In mouse experiments, continuous NMN supplementation significantly increased follicle number and decreased the expression of the senescence hallmark protein p16. The amount of P16 protein increases with age and reduces the ability of cells to divide and proliferate, and thus may serve as an indicator of ovarian senescence. By decreasing the levels of P16 protein, NMN may help to slow down the process of ovarian aging.
NMN promotes the growth and division of ovarian cells and improves the quality of eggs. This is essential for women's reproductive health and fertility. At the same time, NMN can also protect the ovaries from damage caused by free radicals and oxidative stress, and reduce the occurrence of ovarian inflammation, thus maintaining the healthy state of the ovaries.
In addition, NMN regulates the endocrine function of the ovaries and maintains the balance of hormone levels. This is very important for women's reproductive function and overall health. By improving the endocrine environment, NMN may help to promote embryo development and implantation, increasing the success rate of pregnancy.
III. Improvement of a number of postmenopausal health indicators in women
Menopause is a critical stage in a woman's life, accompanied by significant changes in hormone levels and the potential for various discomforts.NMN improves a woman's quality of life by regulating hormone balance and reducing menopausal symptoms such as hot flashes and insomnia.
NMN may also have a positive effect on the prevention of related diseases such as diabetes and cardiovascular disease. By regulating blood sugar and lipid levels, NMN helps to maintain cardiovascular health and reduce the risk of these diseases.
IV. NMN improves sleep quality
NMN is able to regulate the biological clock, making it more stable and adaptable to environmental changes. The biological clock is a natural rhythmic system within the human body, which regulates a variety of physiological activities such as the sleep-wake cycle and body temperature. Studies have shown that fluctuations in NAD+ levels are closely related to the rhythms of the biological clock, and by increasing NAD+ levels, NMN is able to influence the regulation of the biological clock, thus helping to improve sleep quality.
V. Protection of cardiovascular health
Atherosclerosis is an important factor in cardiovascular disease, and NMN exerts its anti-atherosclerotic effects by reducing inflammation and oxidative stress. This helps to prevent the walls of blood vessels from thickening and hardening, maintaining their elasticity and patency.
Additionally, several studies have shown that NMN has the potential to reduce certain aspects of cardiovascular aging. For example, NMN can improve cardiovascular health in overweight individuals and reduce hypertension and arterial stiffness, which are major causes of atherosclerosis.
VI. NMN boosts fertility
NMN significantly restored the quality of oocytes, and it was found that the quality of oocytes was significantly restored by continuous injection of NMN in aged female mice that had experienced a decline in fertility. The uptake of NMN not only boosted the number of eggs, but also improved the quality of the eggs. This restorative effect may contribute to the resolution of impaired fertility due to decreased oocyte quality.
NMN also enhanced the ability of aging oocytes to bind to sperm. In a sperm-oocyte binding assay, researchers found that the fertilisation ability of older oocytes was significantly reduced compared to younger oocytes. However, after supplementation with NMN, the binding ability of older oocytes to sperm was significantly improved. This means that NMN not only enhances the quality of oocytes, but also improves their fertilisation ability and potential for early embryonic development.
In addition, NMN helps restore mitochondrial function in aged oocytes. Mitochondria are the energy factories within the cell and are essential for proper cell function. As we age, mitochondria in oocytes move away from the chromosomes and into the cytoplasm, leading to a decline in their function. NMN supplementation may help to improve the distribution and function of mitochondria, thus further enhancing the health of oocytes.
VII. NMN Aids in Weight Management
SIRT1 is a protein that plays a key role in metabolic regulation and is involved in the management of fat storage and use. When NMN supplementation is taken into the body, the activity of SIRT1 is dramatically boosted to optimise the metabolic state of key proteins and influence mitochondrial function in lipid cells. This alteration helps to eliminate fat accumulation and obesity triggered by abnormal lipid metabolism for healthier weight management.
NMN also increases the activity of the enzyme AMPK, which is involved in cellular energy homeostasis, and NMN may help with weight loss and fight obesity by increasing AMPK activity to promote energy expenditure and fat burning. Additionally, NMN is able to increase the activity of ATGLase, an enzyme that plays a key role in the breakdown of triglycerides (the main type of fat stored in the body). Therefore, NMN may support weight loss by increasing ATGL enzyme activity, promoting the breakdown of stored triglyceride fats and achieving weight loss.
Research also supports the effectiveness of NMN in weight management. A study of middle-aged and older overweight or obese adults found that taking 1,000 mg of NMN twice a day for 28 days resulted in an average weight loss of more than 6 pounds. This result suggests that NMN supplementation can positively contribute to weight management.
VIII. NMN enhances immunity
Immune cells are essential for the body to defend itself against the invasion of external pathogens, and NMN supplementation promotes the proliferation and differentiation of immune cells, enhancing their ability to phagocytose and kill pathogens. This means that the body is able to mobilise immune cells more quickly for defence and attack when faced with infection or disease.
NMN can promote the production of immune factors. Immunokines are important signalling molecules in the immune system that regulate the activity and function of immune cells.NMN promotes the production and release of immunokines by activating specific signalling pathways, thereby enhancing collaboration and communication between immune cells and improving the overall effectiveness of the immune system.
In addition, NMN improves the immune system's ability to respond. When the body is invaded by a pathogen, the immune system needs to respond quickly and accurately to control the infection and prevent the disease from progressing. By optimising the signalling and metabolic processes of the immune cells, NMN enables the immune system to recognise and remove pathogens more quickly, reducing the risk of infection and the duration of disease.
IX. Improving Hair Loss Symptoms
Studies have shown that there is a close correlation between decreased NAD+ levels and hair loss. When the level of NAD+ is insufficient in the cells, it will lead to impaired function of hair follicle cells and affect the hair growth cycle. NMN can improve the metabolic state of hair follicle cells and promote hair growth by supplementing NAD+, thus improving the symptoms of hair loss.
NMN also has antioxidant and anti-inflammatory effects, which also help improve hair loss. Oxidative stress and inflammatory response are important factors in the process of hair loss, and they exacerbate the damage to hair follicle cells, leading to hair loss.By reducing oxidative stress and inhibiting inflammatory response, NMN helps to protect the hair follicle cells from damage and maintains healthy hair growth.
In recent years, scientists have found through research that NMN can promote the growth and vitality of hair follicle cells by increasing intracellular NAD+ levels. The results of a study on mice showed that mice given NMN orally had significantly shorter hair growth cycles, increased hair density, and appeared to have healthier hair morphology. While these results still require further validation and research, the potential of NMN in the prevention and treatment of hair loss is encouraging.
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